Cerebrospinal fluid (CSF) rhinorrhea poses a significant challenge for otolaryngologists and skull-base surgeons, requiring prompt and effective treatment to prevent complications such as meningitis and pneumocephalus.
Causes and Importance of Repair
Skull-base fractures and iatrogenic injuries are the primary causes of CSF rhinorrhea. Repairing these leaks is crucial to prevent potentially serious complications. Endoscopic repair has become the standard approach since its introduction in 1981.
Techniques and Materials Used
Various techniques and materials have been employed for CSF rhinorrhoea repair. These include utilizing septal mucoperiosteum, free grafts from temporalis fascia or fascia lata, free muscle, tragal perichondrium, abdominal fat, or even synthetic dural substitutes. Fibrin glue has been utilized in earlier studies to secure grafts into position.
Challenges and Controversies
While fibrin glue has been used to promote healing, its efficacy in preventing CSF leaks remains a topic of debate. Some studies suggest that fibrin glue may trigger an inflammatory response, potentially aiding in the healing process. However, its use in CSF repair surgery remains controversial.
Comparative Study in Pediatric Patients
Encouraging results from our department prompted a comparative study to assess the efficacy of CSF repair with and without fibrin glue in pediatric patients. This study aims to provide valuable insights into the effectiveness of different repair techniques in this patient population.